Status:
COMPLETED
Multicentre Radial Artery Patency Study: Results of Patency Beyond 5 Years After Coronary Artery Bypass Surgery
Lead Sponsor:
Sunnybrook Health Sciences Centre
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
30-80 years
Phase:
PHASE3
Brief Summary
Bypass surgery is often required to treat severe coronary heart disease. Either arteries or veins can be used as bypass grafts. We wish to compare the long-term durability of the saphenous vein from t...
Detailed Description
The multi-centre Radial Artery Patency Study, (RAPS) is a series of longitudinal graft patency studies designed to compare the long-term patency of the radial artery to the saphenous vein. Between 199...
Eligibility Criteria
Inclusion
- The patient population consists of patients who were enroled into the original Multicentre Radial Artery Patency Study between November 1996 and January 2001. These included patients undergoing isolated coronary artery bypass surgery less than 80 years of age with 3 vessel coronary disease and left ventricular ejection fraction greater than 35%.
Exclusion
- Exclusion criteria included 1: Inability to use the radial artery or saphenous vein conduits: a)nonpalpable ulnar arteries or a positive Allen's test, b) an abnormal Doppler study or ultrasonographic study of the arms, c) a history of vasculitis or Raynaud's syndrome, bilateral varicose veins or vein stripping. 2: Conditions that affected the safety of follow-up angiography: a)renal insufficiency (creatinine \> 180 umol/L) b)severe peripheral vascular disease precluding femoral access b)coagulopathy or obligatory uninterrupted use of anticoagulants c) known allergy to radiographic contrast media d) women of childbearing potential e) comorbid illness which precludes the use of follow up angiography f) geographically inaccessible for follow up angiography.
Key Trial Info
Start Date :
July 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
269 Patients enrolled
Trial Details
Trial ID
NCT00187356
Start Date
July 1 2002
End Date
October 1 2010
Last Update
June 5 2013
Active Locations (13)
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1
University of Alberta
Edmonton, Alberta, Canada, T6G 2B7
2
Manitoba Health Sciences Centre
Winnipeg, Manitoba, Canada, R3A 1R9
3
London Health Sciences Centre - UC
London, Ontario, Canada, N6A 5A5
4
London Health Sciences Centre - VC
London, Ontario, Canada, N6B1B1