Status:
RECRUITING
SCOPE: Observational Study of the Consequences of the Protease Inhibitor Era
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
HIV Infections
Eligibility:
All Genders
18+ years
Brief Summary
SCOPE is an observational, prospective study of HIV-1 infected volunteers designed to provide a specimen bank of samples with carefully characterized clinical data. SCOPE specimens will be used to exa...
Detailed Description
SCOPE is an observational, prospective study of HIV-1 infected volunteers designed to provide a specimen bank of samples with carefully characterized clinical data. Samples from SCOPE will be used to ...
Eligibility Criteria
Inclusion
- SCOPE is currently recruiting HIV-1 infected subjects with any of the following criteria:
- Documented HIV viral load less than 2000 copies/ml WITHOUT taking antiretroviral therapy
- Undetectable HIV viral load with CD4 T-cells consistently less than 350 for the last 12 months while taking a stable antiretroviral regimen.
- Antiretroviral naive and planning to start an antiretroviral regimen - any CD4 or HIV viral load acceptable.
- Long-term Non Progressors: HIV-positive at least 10 years, no antiretroviral therapy for the past 10 years or more, any viral load acceptable, CD4-T cell count always above 500.
Exclusion
- Active opportunistic infection or systemic treatment for opportunistic infection within the last 4 months (oral candidiasis acceptable)
- Active treatment for cancer
- Active treatment for hepatitis C requiring interferon based therapy
- Immunosuppressive therapy taken within the last 4 months
Key Trial Info
Start Date :
March 1 2000
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2033
Estimated Enrollment :
2500 Patients enrolled
Trial Details
Trial ID
NCT00187512
Start Date
March 1 2000
End Date
December 1 2033
Last Update
July 8 2025
Active Locations (1)
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1
San Francisco General Hospital
San Francisco, California, United States, 94110