Status:

COMPLETED

Dexamethasone for Palliation - Brain Metastases

Lead Sponsor:

University Health Network, Toronto

Collaborating Sponsors:

Princess Margaret Hospital, Canada

Conditions:

Neoplasm Metastasis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Brain metastases occur when cancer cells from the initial tumour site (for example, lung or breast) spread to the brain. This develops in approximately 10% - 30% of adults with cancer. They can produc...

Eligibility Criteria

Inclusion

  • Known diagnosis of cancer (even if primary unknown)
  • Brain metastases (single or multiple) confirmed by imaging (CT, MRI)
  • No contraindication for RT/steroids
  • Patient will be treated with Whole Brain Radiation Therapy
  • Informed consent

Exclusion

  • Primary cancer is lymphoma or leukemia
  • Complete surgical excision of brain metastases
  • Patient was on steroids for more then 2 weeks prior to entering the study
  • Confusion or other factors that would impair ability to assess symptoms

Key Trial Info

Start Date :

November 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 28 2019

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00188864

Start Date

November 1 2003

End Date

January 28 2019

Last Update

November 27 2019

Active Locations (1)

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Princess Margaret Hospital

Toronto, Ontario, Canada, M5G 2M9