Status:
UNKNOWN
Dutch Prediction of Psychosis Study
Lead Sponsor:
UMC Utrecht
Collaborating Sponsors:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
ZonMw: The Netherlands Organisation for Health Research and Development
Conditions:
Psychotic Disorders
Eligibility:
All Genders
12-18 years
Brief Summary
The Dutch Prediction of Psychosis Study (DUPS) is a prospective study of predictors of the transition to psychosis in help-seeking adolescents at high risk for developing a first psychotic episode. Th...
Detailed Description
The Dutch Prediction of Psychosis Study (DUPS) is a collaboration of the Academic Medical Center in Amsterdam (AMC) and the University Medical Center in Utrecht (UMC). The main objectives are: 1. Pat...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Help-seeking adolescents who belong to one or more of the following groups:
- Basic symptoms: presence of self-perceived cognitive thought disturbances
- Familial risk plus reduced functioning: having a first- or second degree relative with a history of any psychotic disorder in combination with a deterioration of mental state and/or social functioning in the last year
- Attenuated psychotic symptoms: presence of psychotic symptoms at sub-clinical level
- Brief, limited or intermittent psychotic symptoms: having a history of psychotic symptoms with a duration of less than one week and spontaneous remission
- Multiple Complex Developmental disorder
- Exclusion criteria:
- A previous psychotic episode for more than one week
- Verbal IQ \< 75
- Symptoms are due to an organic mental disorder or substance abuse
Exclusion
Key Trial Info
Start Date :
June 1 2003
Trial Type :
OBSERVATIONAL
End Date :
June 1 2008
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00188981
Start Date
June 1 2003
End Date
June 1 2008
Last Update
April 20 2007
Active Locations (1)
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1
University Medical Center Utrecht, department of Child and Adolescent Psychiatry
Utrecht, Utrecht, Netherlands