Status:
COMPLETED
ECLAXIR:Search for an Association Between CX3CR1 V249I Polymorphism, Preeclampsia and Endothelial Injury
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Preeclampsia
Eligibility:
FEMALE
Brief Summary
The study hypothesis is the involvement of the couple CX3CR1/CX3CL1 in occurrence of endothelial injury in preeclampsia. According to this hypothesis, Carriers of the I249 allele who express less CX3C...
Detailed Description
It is a case-control multicenter study 185 caucasian pregnant women with preeclampsia and 185 paired controls without preeclampsia will be included. The frequency of the V249I polymorphism in african...
Eligibility Criteria
Inclusion
- cases: pregnant woman, evolutive pregnancy, preeclampsia, caucasian, consenting to the study
Exclusion
- Cases:
- multiple pregnancy, proteinuria \> 300 mg/24h before 21th gestation week.
Key Trial Info
Start Date :
March 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2007
Estimated Enrollment :
370 Patients enrolled
Trial Details
Trial ID
NCT00190177
Start Date
March 1 2003
End Date
October 1 2007
Last Update
October 18 2013
Active Locations (1)
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1
Hôpital Louis Mourier AP-HP
Colombes, France, 92701