Status:
TERMINATED
Assessing Repetitive Transcranial Magnetic Stimulation as a Treatment for Refractory Depression (rTMS)
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Institut National de la Santé Et de la Recherche Médicale, France
International Atomic Energy Agency
Conditions:
Depression
Eligibility:
All Genders
18-55 years
Phase:
PHASE3
Brief Summary
The hypothesis of this study was that transcranial magnetic stimulation (TMS) focused on hyperfunctional cerebral areas should be more effective in treating depressive symptoms than stimulations not t...
Detailed Description
The objectives of the study were : * To localize the site of lowest frontal activity in each patient with resistant depression, using PET to measure regional cerebral metabolic rates for glucose (rCM...
Eligibility Criteria
Inclusion
- Major depression (according to DSM-IV)resistant to at least two medical antidepressant treatment of different pharmacological action, prescribed for at least one month each at an effective dosage, without therapeutical result.
- Hospitalisation in the service of an investigator
- Informed consent signed
Exclusion
- Presence of metallic parts inside the body (pace-maker, vascular clip, cardiac valve, prothesis...)
- Severe somatic or central nervous system disease
- Familial history of comitiality
- Pregnancy
Key Trial Info
Start Date :
December 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2007
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00190216
Start Date
December 1 2001
End Date
October 1 2007
Last Update
November 8 2007
Active Locations (1)
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1
Albert Chenevier Hospital, Department of psychiatry
Créteil, France, 94000