Status:

COMPLETED

The Effect of Ruboxistaurin on Small Fiber Function

Lead Sponsor:

Chromaderm, Inc.

Conditions:

Diabetic Neuropathy

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

To determine the effect of Ruboxistaurin on small fiber function.

Eligibility Criteria

Inclusion

  • Patients must have Type 1 or Type 2 diabetes mellitus
  • Patients must have bilateral sensorimotor distal peripheral neuropathy attributable to diabetes mellitus
  • Patients must have blood glucose control measured as HbA1c=\<11%
  • Patients must be 18 years of age or older.
  • Patients must be able to return to all follow-up visits

Exclusion

  • Patients must not have symptoms of diabetic peripheral neuropathy that cannot be distinguished from other etiologies
  • Patients must not have a neurologic disease or neuropathy from a cause other than diabetes mellitus that would interfere with correct evaluation of symptomatic peripheral neuropathy.
  • Patient currently has uncontrolled high blood pressure
  • You have other medical problems that your doctor feels would make it unsafe for you to participate in this study such as liver or kidney problems
  • You are a woman of childbearing age and unwilling or unable to use effective contraceptive.

Key Trial Info

Start Date :

October 1 2004

Trial Type :

INTERVENTIONAL

End Date :

November 1 2005

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT00190970

Start Date

October 1 2004

End Date

November 1 2005

Last Update

July 26 2016

Active Locations (1)

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Monday-Friday from 9:00 AM to 5:00 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician

Norfolk, Virginia, United States