Status:
UNKNOWN
Three Field Radical Esophagectomy Versus Two Field Esophagectomy - a Prospective Trial
Lead Sponsor:
Tata Memorial Hospital
Conditions:
Cancer of Esophagus
Eligibility:
All Genders
18-70 years
Phase:
PHASE3
Brief Summary
Surgery is the standard treatment for esophageal (food pipe) cancer. Esophageal cancer is known to spread to the lymph nodes (glands) adjacent to the esophagus. The extent of lymph nodes that need to ...
Detailed Description
Three field radical esophagectomy versus two field esophagectomy - a prospective randomized controlled trial Background Esophageal cancer is a common problem worldwide and is associated with poor pro...
Eligibility Criteria
Inclusion
- Patients with biopsy or cytology proven (squamous or adenocarcinoma) esophageal cancer
- Patients with staging investigations showing operability
- Surgical plan of total transthoracic esophagectomy
Exclusion
- Patients with low performance status (ECOG score\>1)
- Past history of malignancy
- Staging investigations indicating advanced disease
- Patients medically unfit for surgical resection
- Patients with pulmonary reserve inadequate to undergo thoracotomy and extensive mediastinal lymphadenectomy
- Patients considered for salvage surgery after definitive (radical)chemoradiotherapy
- Patients with supracarinal lymph node enlargement on CT scan and/or EUS
- Patients intraoperatively detected to have grossly enlarged supracarinal lymph nodes
- Patients with Siewert's type III CO junction growths
- Patients above the age of 70 years
- Patients unreliable for follow up
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
End Date :
December 1 2015
Estimated Enrollment :
700 Patients enrolled
Trial Details
Trial ID
NCT00193817
Start Date
January 1 2005
End Date
December 1 2015
Last Update
February 7 2006
Active Locations (1)
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1
Tata Memorial Hospital
Mumbai, Maharashtra, India, 400012