Status:
COMPLETED
Factor V Leiden Mutation and Implantation Failure
Lead Sponsor:
University of Pennsylvania
Conditions:
Infertility
Eligibility:
FEMALE
18+ years
Brief Summary
The purpose of this study is to determine whether inherited thrombophilias (tendency toward blood clotting) increase the risk of failure of the embryo to implant in IVF. The specific condition to be s...
Eligibility Criteria
Inclusion
- Women undergoing in-vitro fertilization with successful ovarian hyperstimulation, oocyte retrieval, and fertilization
- Transfer of at least 2 fresh embryos of Grade 2 (preembryo with blastomeres of equal size and \<=10% cytoplasmic fragmentation) or better
Exclusion
- Infertility due to uterine anatomic defect
- Current use of anticoagulant medication, such as heparin or aspirin
- Known presence of any other condition associated with increased risk of thrombosis
Key Trial Info
Start Date :
September 1 2001
Trial Type :
OBSERVATIONAL
End Date :
August 1 2005
Estimated Enrollment :
399 Patients enrolled
Trial Details
Trial ID
NCT00194350
Start Date
September 1 2001
End Date
August 1 2005
Last Update
August 9 2011
Active Locations (1)
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1
University of Pennsylvania Reproductive Research Unit
Philadelphia, Pennsylvania, United States, 19104