Status:
COMPLETED
Safety and Efficacy Study of Hydromorphone and Morphine
Lead Sponsor:
Montefiore Medical Center
Conditions:
Pain
Eligibility:
All Genders
21-65 years
Phase:
PHASE2
Brief Summary
To compare a standard weight-based dose of intravenous (IV) hydromorphone (Dilaudid) to a standard weight-based dose of IV morphine in adults presenting to the Emergency Department (ED) with acute sev...
Detailed Description
There is widespread agreement that pain is under-treated in the Emergency Department (ED). The current recommended treatment of acute pain in the ED setting is administration of an initial bolus of mo...
Eligibility Criteria
Inclusion
- adults between the ages of 21 and 65 who presented to the ED with acute pain (defined as pain less than 7 days in duration) (23) of sufficient severity in the judgment of the ED attending to warrant use of IV opioids.
Exclusion
- previous allergy to morphine or hydromorphone
- systolic blood pressure less than 90 mmHg
- alcohol intoxication as judged by the attending physician
- use of other opioids within the past 7 days
- use of an Monoamine Oxidase (MAO) inhibitor
- chronic pain syndromes (such as sickle cell disease or fibromyalgia)
Key Trial Info
Start Date :
October 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2005
Estimated Enrollment :
198 Patients enrolled
Trial Details
Trial ID
NCT00195910
Start Date
October 1 2004
End Date
January 1 2005
Last Update
August 15 2018
Active Locations (1)
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1
Montefiore Medical Center
The Bronx, New York, United States, 10467