Status:
COMPLETED
Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis
Lead Sponsor:
Children's Mercy Hospital Kansas City
Conditions:
Perforated Appendicitis
Eligibility:
All Genders
1-18 years
Brief Summary
The purpose of this study is to compare traditional triple antibiotic therapy against dual single day dosing antibiotic therapy in the management of perforated appendicitis in children.
Detailed Description
Triple antibiotic therapy providing broad spectrum coverage of gram positive, gram negative and anaerobic bacteria has long been the standard treatment for perforated appendicitis in children. This re...
Eligibility Criteria
Inclusion
- All patients under 18 years of age found to have perforated appendicitis at the time of operation for appendicitis and whose parents give informed permission will be included in the study.
Exclusion
- Patients with a normal or non-perforated appendix at the time of appendectomy, those without parental permission, or those with a documented allergy to any of the antibiotics used in either regimen will be excluded from the study. Patients 18 years or older will not be included in the study
Key Trial Info
Start Date :
April 1 2005
Trial Type :
OBSERVATIONAL
End Date :
January 1 2007
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00195923
Start Date
April 1 2005
End Date
January 1 2007
Last Update
April 6 2007
Active Locations (1)
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1
The Children's Mercy Hospital
Kansas City, Missouri, United States, 64108