Status:
COMPLETED
Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic Rickets
Lead Sponsor:
Children's Mercy Hospital Kansas City
Conditions:
Hypophosphatemic Rickets, X-Linked Dominant
Eligibility:
All Genders
5+ years
Phase:
PHASE1
Brief Summary
This study will measure the effect of cinacalcet (Sensipar) on parathyroid hormone (PTH) secretion in children and adolescents with hypophosphatemic rickets (XLH). The investigators are seeking eviden...
Detailed Description
X-linked hypophosphatemic rickets (XLH) is an X-linked dominant genetic disorder. Common findings are low serum phosphate and inadequate 1,25(OH)2 vitamin D production. It is generally believed that t...
Eligibility Criteria
Inclusion
- Established patients with XLH
- Age 5 years old and above
- Normal serum calcium and creatinine concentrations
Exclusion
- Patients with hypersensitivity to any component(s) of cinacalcet
- Hypocalcaemia
- Elevated serum creatinine
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2008
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT00195936
Start Date
June 1 2005
End Date
February 1 2008
Last Update
January 19 2021
Active Locations (1)
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1
Section of Pediatric Nephrology, Children's Mercy Hospitals and Clinics
Kansas City, Missouri, United States, 64108