Status:

UNKNOWN

Line Versus Spot Ablation in Persistent Atrial Fibrillation

Lead Sponsor:

Deutsches Herzzentrum Muenchen

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

In this randomized study dealing with the ablative treatment of persistent atrial fibrillation, two ablation strategies are compared: a more anatomically guided linear ablation scheme versus an electr...

Detailed Description

This randomized study deals with two different ablative treatment strategies for persistent atrial fibrillation: a more anatomically guided linear ablation scheme with encircling of the ipsilateral pu...

Eligibility Criteria

Inclusion

  • age between 18 and 80 years
  • symptomatic persistent (\> 7 days lasting) atrial fibrillation
  • at least one unsuccessful cardioversion or atrial fibrillation relapse in the first 3 months after cardioversion despite antiarrhythmic drug therapy
  • oral anticoagulation (\> 4 weeks prior to ablation)

Exclusion

  • moderate to severe valvular heart disease
  • congenital heart disease
  • LV-EF \< 35%
  • reversible cause for atrial fibrillation (e.g., hyperthyreosis)
  • prior left atrial ablation or Maze operation
  • left atrial thrombus

Key Trial Info

Start Date :

August 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2008

Estimated Enrollment :

116 Patients enrolled

Trial Details

Trial ID

NCT00196157

Start Date

August 1 2004

End Date

November 1 2008

Last Update

May 29 2009

Active Locations (1)

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Deutsches Herzzentrum Muenchen

Munich, Germany, 80636