Status:

COMPLETED

Trigger- vs. Substrate-Ablation for Paroxysmal Atrial Fibrillation

Lead Sponsor:

Deutsches Herzzentrum Muenchen

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to compare two strategies of catheter-based treatment of paroxysmal atrial fibrillation: Pulmonary vein isolation either alone or combined with electrogram-guided substrat...

Detailed Description

Catheter ablation has evolved an accepted alternative in the curative treatment of atrial fibrillation (AF). However, discussion about the best ablation strategy is still ongoing. In patients with pa...

Eligibility Criteria

Inclusion

  • Age \> 18 and \<80 years
  • Symptomatic paroxysmal atrial fibrillation
  • Drug-refractory
  • Anticoagulation

Exclusion

  • Hyperthyreosis
  • Moderate-to-severe mitral valve valvulopathy
  • LV-ejection fraction \<35%
  • Prior ablation, PCI or heart surgery \<3 months
  • Left atrial thrombus

Key Trial Info

Start Date :

August 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2006

Estimated Enrollment :

98 Patients enrolled

Trial Details

Trial ID

NCT00196183

Start Date

August 1 2004

End Date

June 1 2006

Last Update

March 18 2008

Active Locations (1)

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Deutsches Herzzentrum Muenchen

Munich, Germany, 80636