Status:

COMPLETED

Salvage Therapy With Amprenavir, Lopinavir and Ritonavir in HIV-Infected Patients in Virological Failure.

Lead Sponsor:

French National Agency for Research on AIDS and Viral Hepatitis

Conditions:

HIV Infections

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

HIV infected patients are treated with highly active antiretroviral therapy (HAART). Side effects and the great number of pills reduces adherence to the treatment, and induces therapeutic failure. In ...

Detailed Description

HIV infected patients are treated with highly active antiretroviral therapy (HAART). Side effects and the great number of pills reduces adherence to the treatment, and induces therapeutic failure. In ...

Eligibility Criteria

Inclusion

  • Documented HIV infection
  • CD4 cell count below 300/mm3
  • Plasma HIV RNA over 30,000 copies/ml
  • Previously treated with 2 protease inhibitors and 1 non nucleoside analogue (except amprenavir, lopinavir)
  • Written informed consent

Exclusion

  • Biological abnormalities
  • Pregnancy
  • Alcool abuse
  • History of pancreatitis, hepatic failure
  • Acute HIV related infection
  • Chemotherapy

Key Trial Info

Start Date :

November 1 2000

Trial Type :

INTERVENTIONAL

End Date :

February 1 2002

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00196625

Start Date

November 1 2000

End Date

February 1 2002

Last Update

September 20 2005

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