Status:

COMPLETED

An Extension of Istradefylline in Parkinson's Disease Patients Who Have Completed Studies 6002-EU-007, 6002-US-013 or 6002-US-018

Lead Sponsor:

Kyowa Kirin, Inc.

Collaborating Sponsors:

Kyowa Hakko Kirin UK, Ltd.

Conditions:

Parkinson's Disease

Eligibility:

All Genders

30+ years

Phase:

PHASE3

Brief Summary

This is a 1-year, open-label, long-term safety extension for patients who have completed prior istradefylline studies 6002-EU-007, 6002-US-013 or 6002-US-018.

Detailed Description

Patients with Parkinson's disease with motor complications on levodopa therapy who completed the prior double-blind studies 6002-EU-007, 6002-US-013 or 6002-US-018 are eligible to enter into this 1-ye...

Eligibility Criteria

Inclusion

  • Completion of study 6002-EU-007, 6002-US-013 or 6002-US-018
  • Non-pregnant and either not of childbearing potential or using specified contraception

Exclusion

  • History of psychotic illness
  • Variant/atypical Parkinson's disease
  • Cancer within 5 years of enrollment
  • ALT/AST levels \> 1.5 times ULN
  • Seizure disorder
  • Neuroleptic malignant syndrome

Key Trial Info

Start Date :

October 1 2004

Trial Type :

INTERVENTIONAL

End Date :

May 1 2007

Estimated Enrollment :

1100 Patients enrolled

Trial Details

Trial ID

NCT00199368

Start Date

October 1 2004

End Date

May 1 2007

Last Update

April 25 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Kyowa Pharmaceutical Inc.

Princeton, New Jersey, United States, 08540