Status:
COMPLETED
Effectiveness of a Low Carbohydrate Diet Versus a High Carbohydrate Diet in Promoting Weight Loss and Improved Health
Lead Sponsor:
Kaiser Permanente
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Obesity
Hypertension
Eligibility:
All Genders
21+ years
Phase:
PHASE2
Brief Summary
This study will examine the effects of a low carbohydrate diet versus a high carbohydrate diet on weight loss.
Detailed Description
The number of overweight and obese Americans has increased significantly in recent years. There are now many different diet plans being promoted by doctors and the media. The Atkins diet, a low carboh...
Eligibility Criteria
Inclusion
- Body mass index (BMI) of 27 to 50
- Fasting glucose less than 126 mg/dl
- Total fasting cholesterol less than 260 mg/dl
- Total fasting triglycerides less than 400 mg/dl
- Permission of primary care provider to participate in the study
- Normal liver and kidney function
- Willing to modify diet and other health behaviors
- Willing to use an acceptable method of contraception for the duration of the study
Exclusion
- Any medical condition that may make weight loss medically inadvisable
- Weigh more than 400 lbs
- History of kidney failure
- Current use of more than 3 blood pressure medications
- Change in blood pressure medications within 3 months prior to study entry
- Diagnosis of cardiovascular disease within 6 months prior to study entry
- Cancer diagnosis within 2 years of study entry. Participants with basal cell skin cancer are not excluded.
- History of psychiatric hospitalization within 2 years prior to study entry
- Consumption of more than three alcoholic drinks a day
- Type I or II diabetes
- Current use of hypolipidemics, antipsychotics, hypoglycemics, glucocorticoids, or thyroid medication
- Plan to move during study
- Current participation in another clinical trial
- Pregnancy or breastfeeding
Key Trial Info
Start Date :
April 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
260 Patients enrolled
Trial Details
Trial ID
NCT00200720
Start Date
April 1 2005
End Date
June 1 2010
Last Update
December 6 2012
Active Locations (1)
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1
Kaiser Permanente Center for Health Research
Portland, Oregon, United States, 97227