Status:
COMPLETED
Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis.
Lead Sponsor:
Frédéric A. Houssiau, MD, PhD
Conditions:
Lupus Nephritis
Eligibility:
All Genders
14+ years
Phase:
PHASE3
Brief Summary
The purpose of the study is to determine whether mycophenolate mofetil is superior to azathioprine to prevent flares of lupus nephritis.
Detailed Description
Proliferative glomerulonephritis is a common and severe manifestation of systemic lupus erythematosus (SLE) that usually requires intensive therapy with high doses of glucocorticosteroids and cytotoxi...
Eligibility Criteria
Inclusion
- SLE aged ≥ 14 years
- Proteinuria ≥ 500 mg/day
- Biopsy-proven proliferative lupus nephritis
Exclusion
- Recent treatment with high-dose glucocorticoids
- Recent treatment with immunosuppressive drugs
- More exclusion criteria in the protocol
Key Trial Info
Start Date :
February 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT00204022
Start Date
February 1 2001
End Date
August 1 2011
Last Update
October 14 2011
Active Locations (1)
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1
Université catholique de Louvain
Brussels, Belgium, B-1200