Status:

COMPLETED

A Comparison of Symbicort® pMDI 2 x 160/4.5 μg Bid and Symbicort® pMDI 2 x 80/4.5 μg Bid With Formoterol Turbuhaler®, Budesonide pMDI, the Combination of Formoterol Turbuhaler® and Budesonide pMDI, and Placebo in COPD Patients

Lead Sponsor:

AstraZeneca

Conditions:

Chronic Obstructive Pulmonary Disease

Eligibility:

All Genders

40+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to compare a combination asthma drug (Symbicort) with its two components, budesonide and formoterol, taken individually or in combination, and with placebo in the long-ter...

Eligibility Criteria

Inclusion

  • A clinical diagnosis of COPD with symptoms for more than 2 years
  • Smoking history of 10 or more pack years
  • A history of at least one COPD exacerbation requiring a course of oral steroids and/or antibiotics within 1-12 months before first visit.

Exclusion

  • A history of asthma
  • Patients taking oral steroids.
  • Any significant disease or disorder that may jeopardize the safety of the patient

Key Trial Info

Start Date :

April 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2006

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT00206154

Start Date

April 1 2005

End Date

December 1 2006

Last Update

March 27 2009

Active Locations (212)

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Page 1 of 53 (212 locations)

1

Research Site

Birmingham, Alabama, United States

2

Research Site

Jasper, Alabama, United States

3

Research Site

Mobile, Alabama, United States

4

Research Site

Glendale, Arizona, United States