Status:
UNKNOWN
The Role of Naive T-Cells in HIV Pathogenesis
Lead Sponsor:
Bayside Health
Conditions:
HIV Infections
Eligibility:
All Genders
Brief Summary
While HIV mainly infects mature T-cells it can also infect newly produced (or naïve) T-cells. These infected naïve T cells may then act a viral reservoir even in patients with undetectable viral loads...
Detailed Description
The overall goal of this project is to provide a comprehensive analysis of the role of naïve T-cells in the pathogenesis of T-cell decline and long-term persistence of HIV infection. The study is div...
Eligibility Criteria
Inclusion
- \-
- Part 1:
- \- HIV positive by ELISA and Western Blot VL \>2,000, CD4 \>350
- Part 2:
- HIV positive by ELISA and Western Blot
- Established Chronic infection (15 individuals)
- Acute infection (15 individuals).
- Any viral load or CD4 count.
- No therapy.
- Any individual who initiates HAART as determined by the treating physician
Exclusion
- none
Key Trial Info
Start Date :
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT00206531
Last Update
October 4 2006
Active Locations (1)
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1
Alfred Hospital
Melbourne, Victoria, Australia, 3004