Status:
COMPLETED
Study of Unilateral Neck Irradiation in Patients With SCC of the Head and Neck
Lead Sponsor:
Beth Israel Medical Center
Conditions:
Squamous Cell Carcinoma of the Head and Neck
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to assess the feasibility of avoiding opposite side neck radiation therapy in patients with clearly one side squamous cell cancer of the head and neck. We aim to assess th...
Detailed Description
Patients will be treated with definitive external beam radiation plus/minus chemotherapy plus/minus neck dissection in the ipsilateral neck (post radiation). The primary site will be treated with defi...
Eligibility Criteria
Inclusion
- Squamous cell carcinoma of the oral cavity or oropharynx, with the primary lesion \>1 cm from the midline.
- Patient has no clinical or radiologic evidence of contralateral neck node metastases.
- No evidence of distant metastasis.
- No previous history of radiation therapy or chemotherapy
- performance status 0-2
- Age \>= 18
- Signed informed consent
- Patients must be accessible for treatment and follow-up
Exclusion
- HIV positive patients
- Pregnancy or any patients not practicing contraception
- Active tobacco or alcohol addiction (as assessed by medical caregiver)
- Serious comorbid disease which prevents delivery of full treatment including psychiatric disorders, cardiopulmonary disease, etc.
- Concomitant use of any trial anticancer therapeutic within 30 days of entry
- Uncontrolled hypertension
- Known hypersensitivity to mammalian cell-derived products
Key Trial Info
Start Date :
August 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT00206752
Start Date
August 1 2004
End Date
February 1 2015
Last Update
March 30 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Beth Israel Medical Center
New York, New York, United States, 10003