Status:
COMPLETED
The Effects of Increased Central Serotonergic Activity on Information Processing
Lead Sponsor:
University of Copenhagen
Collaborating Sponsors:
Lundbeck Foundation
Glostrup University Hospital, Copenhagen
Conditions:
Healthy Volunteers
Eligibility:
MALE
18-35 years
Phase:
NA
Brief Summary
It is of great clinical relevance to know if selective serotonin re-uptake inhibitors affect information processing. Our hypothesis was that aspects of information processing would be disturbed wherea...
Detailed Description
Numerous studies point to an increased serotoninergic activity in schizophrenia. Additionally, patients with schizophrenia often show reduced filtering of sensory information, which is reflected in re...
Eligibility Criteria
Inclusion
- Male subjects
- Good Physical and Mental Health meeting criteria "never mentally ill", which will be evaluated with a medical history checklist, ECG
- Non smokers
Exclusion
- Current use of any medication
- Any subject who has received any investigational medication within 30 days prior to the start of this study
- History of neurologic illness
- History of psychiatric illness in first-degree relatives, evaluated with DSM-IV criteria
- History of alcohol and drug abuse. Positive urine screening for amphetamine, cocaine, cannabis, or esctacy.
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2006
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00206934
Start Date
March 1 2005
End Date
March 1 2006
Last Update
September 19 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Center for Neuropsychiatric Schizophrenia Research, University of Copenhagen, Psychiatric Center Glostrup
Glostrup Municipality, Denmark, DK-2600