Status:

COMPLETED

Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia

Lead Sponsor:

Columbia University

Collaborating Sponsors:

Solstice Neurosciences

Conditions:

Focal Dystonia

Eligibility:

All Genders

25-69 years

Phase:

PHASE4

Brief Summary

This study uses a computerized method of musical instrument digital interface (MIDI) quantification of performance before and after treatment with botulinum toxin type B (Myobloc ®, Solstice Neuroscie...

Detailed Description

Dystonia represents a group of clinical disorders characterized by various combinations of sustained involuntary muscle contractions, abnormal postures and movements, tremors and pain. Dystonia can oc...

Eligibility Criteria

Inclusion

  • Focal, task-specific dystonia clinically determined to be the result of a high level of musical skill and intensive performance history

Exclusion

  • Neurological disorders other than dystonia
  • Patients who are clinically depressed, demented or otherwise unable to perform appropriately or sit through 1 hour of testing
  • Patients who have undergone pallidotomy, thalamotomy or deep brain stimulator implantations
  • Patients who have who recently have taken medications with extrapyramidal or tremorogenic side effects

Key Trial Info

Start Date :

April 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2008

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT00208091

Start Date

April 1 2003

End Date

May 1 2008

Last Update

May 9 2014

Active Locations (1)

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1

Neurological Institute, 710 W. 168th Street, NI-1112

New York, New York, United States, 10032