Status:
COMPLETED
Calcium and Vitamin D vs Markers of Adenomatous Polyps
Lead Sponsor:
Emory University
Collaborating Sponsors:
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Conditions:
Colorectal Adenomatous Polyps
Eligibility:
All Genders
30-74 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to test whether calcium and/or vitamin D supplementation favorably affects a set of biomarkers of risk for colon cancer in persons who are at higher than average risk for ...
Detailed Description
There is strong biologic plausibility and animal experimental evidence for protection against colorectal cancer by calcium and vitamin D, calcium significantly reduced adenoma recurrence in a large cl...
Eligibility Criteria
Inclusion
- age 30-74
- adenomatous colon polyp within past 3 years
- general good health with life expectancy of at least 2 years
- available for 8 months and able to come for clinic visits
Exclusion
- cancer within 5 years
- active major disease
- renal impairment
- history of kidney stones
- significant dietary change or weight loss within past 6 months
- unable to forego usual calcium or vitamin D use during study
Key Trial Info
Start Date :
May 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT00208793
Start Date
May 1 2005
End Date
February 1 2013
Last Update
November 26 2013
Active Locations (1)
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1
The Emory Clinic, Division of Digestive Diseases
Atlanta, Georgia, United States, 30322