Status:
COMPLETED
Effect of Paracetamol,Pregabalin and Dexamethasone on Pain and Opioid Requirements in Postoperative Patients
Lead Sponsor:
Glostrup University Hospital, Copenhagen
Conditions:
Pain, Postoperative
Eligibility:
FEMALE
18-75 years
Phase:
PHASE4
Brief Summary
Women scheduled for abdominal hysterectomy needs postoperative pain treatment, i.e. morphine. Unfortunately morphine has side-effect: nausea, vomiting, sedation and dizziness, which is unpleasant for ...
Detailed Description
Combinations of paracetamol versus paracetamol + pregabalin versus paracetamol + pregabalin + dexamethasone is investigated. Primary outcome is 24 hours morphine usage.
Eligibility Criteria
Inclusion
- Women scheduled for abdominal hysterectomy, between the age of 18 and 75, ASA 1-2
- BMI between 18-32.
Exclusion
- Patients who:
- Are unable to cooperate
- Has cancer ovarian
- Does not speak Danish
- Has allergy for drugs used in the trial
- Has drug and medicine abuse
- Epilepsy
- Diabetes treated with medicine
- Chronic pain condition
- Daily use of antacids or analgesic
- Known kidney disease
- Use of antidepressive
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2008
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00209495
Start Date
June 1 2005
End Date
February 1 2008
Last Update
February 29 2008
Active Locations (2)
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1
Operations og Anæstesiologisk afd. Y, KAS Glostrup
Glostrup Municipality, Copenhagen, Denmark, 2600
2
Herning Centralsygehus
Herning, Denmark, 7400