Status:

COMPLETED

A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation.

Lead Sponsor:

Alza Corporation, DE, USA

Conditions:

Ejaculation

Eligibility:

MALE

18+ years

Phase:

PHASE3

Brief Summary

The primary purpose of the study is to demonstrate that dapoxetine can prolong intravaginal ejaculatory latency time (IELT) compared with placebo in men with premature ejaculation (PE).

Detailed Description

One form of male sexual dysfunction is premature ejaculation (PE), which is also referred to as rapid ejaculation (RE). An objective measurement of PE in clinical studies is the intravaginal ejaculato...

Eligibility Criteria

Inclusion

  • Heterosexual male in a stable, monogamous, sexual relationship with a female partner for at least 6 months
  • onset of orgasm and ejaculation occurs with minimal sexual stimulation before or shortly after penetration and before the person wishes it
  • premature ejaculation (PE) in the majority of intercourse experiences in the 6 months before study initiation
  • intravaginal latency ejaculatory time (IELT) of \<=2 minutes in at least 3 out of 4 events
  • participants with partners of child-bearing potential must consent to use a medically acceptable method of contraception throughout the entire study
  • participant's partner must have a negative pregnancy test at time of screening.

Exclusion

  • History of surgery or injury to the pelvis or spinal cord, chronic inflammation of the prostate or urethra
  • taking medications that are contraindicated for participation in the study
  • currently using other forms of therapy for treatment of PE (for example, behavioral therapy or medications applied locally)
  • previously participated in a drug study involving dapoxetine or in another drug trial within the last month
  • taken pimozide, astemizole, or monoamine oxidase inhibitors within 6 months of the start of the study.

Key Trial Info

Start Date :

June 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2004

Estimated Enrollment :

1294 Patients enrolled

Trial Details

Trial ID

NCT00211107

Start Date

June 1 2003

End Date

June 1 2004

Last Update

May 19 2011

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