Status:
COMPLETED
Photodynamic Therapy Using Verteporfin for Treatment of Chronic Central Serous Chorioretinopathy (CSC)
Lead Sponsor:
Manhattan Eye, Ear & Throat Hospital
Conditions:
Chronic Central Serous Chorioretinopathy
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Central serous choroidal (CSC) retinopathy is a disease of the macula characterized by exudation of fluid under the retina localized to the posterior pole as well as loss of vision. The etiology is un...
Detailed Description
7.1 Visit 1 - Screening Visit The first visit by the patient is for the purpose of screening the patient for the study. This visit must occur within 1 week prior to the treatment visit. At this visit...
Eligibility Criteria
Inclusion
- Evidence of chronic central serous chorioretinopathy and clinical/angiographic findings typical of the disease of greater than 6 months duration.Chronic central serous chorioretinopathy could be defined on the basis of two factors: a) persistence of the detachment for more than 6 months and b) chronic recurrent acute detachments with widespread decompensation of the retinal pigment epithelium.
- VA 20/40 and 20/320 Study Eye on the ETDRS visual acuity chart.
- VA 20/800 or better Fellow Eye on the ETDRS visual acuity chart.
Exclusion
- Patient with tears in retinal pigment epithelium.
- Patient with significantly compromised visual acuity in the study eye due to concomitant ocular conditions.
- Patients who have undergone intraocular surgery within last 2 months or capsulotomy within last month in study eye.
- Patient participating in any other investigational drug study.
- Inability to obtain photographs to document CNV (including difficulty with venous access).
- Patient with significant liver disease or uremia.
- Patient with known adverse reaction to indocyanine green or iodine.
- Patient is pregnant or nursing
- Age less than 18 years old
Key Trial Info
Start Date :
July 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2006
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT00211445
Start Date
July 1 2002
End Date
January 1 2006
Last Update
September 28 2007
Active Locations (1)
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1
Manhattan Eye, Ear & Throat Hospital
New York, New York, United States, 10021