Status:
COMPLETED
Follow-up Modalities of Low Grade Precancerous Bronchial Lesions
Lead Sponsor:
University Hospital, Rouen
Conditions:
Precancerous Conditions
Thoracic Neoplasms
Eligibility:
All Genders
18-80 years
Brief Summary
The goal of this multicentric French randomized trial is to determine the best auto fluorescence bronchial endoscopic follow-up strategy in high risk patients bearing low grade bronchial precancerous ...
Detailed Description
The goal of this multicentric French randomized trial is to determine the best auto fluorescence bronchial endoscopic follow-up strategy in high risk patients bearing low grade bronchial precancerous ...
Eligibility Criteria
Inclusion
- Patient with one or several of the following risk factor for lung cancer:
- Tobacco consumption more than 30 pack years
- Lung or ENT cancer history, cured
- Occupational exposure to respiratory carcinogens
- Normal baseline CT scan
- Autofluorescence endoscopy showing moderate dysplasia or lower grade lesion
- Written informed consent
Exclusion
- Treatment with Vit A derivative
- Contra indication for a fiberoptic bronchoscopy under local anesthesia.
- Known evolutive cancer
- Chest radiation therapy within 5 years before inclusion or chemotherapy within two years before inclusion.
- Impossibility for a 3 years follow-up
Key Trial Info
Start Date :
April 1 2002
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2009
Estimated Enrollment :
365 Patients enrolled
Trial Details
Trial ID
NCT00213603
Start Date
April 1 2002
End Date
November 1 2009
Last Update
January 18 2013
Active Locations (1)
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1
Rouen University Hospital
Rouen, Haute Normandie, France, 76000