Status:

COMPLETED

A Study to Evaluate the Efficacy and Safety of an Experimental Solution for Peritoneal Dialysis

Lead Sponsor:

Vantive Health LLC

Collaborating Sponsors:

Baxter Healthcare Corporation

Conditions:

End Stage Renal Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Objective: The purpose of this study is to demonstrate: -the non-inferiority of an experimental peritoneal dialysis solution compared to a current solution for the management of end stage renal disea...

Eligibility Criteria

Inclusion

  • Patients who have given written informed consent after the nature of the study has been explained.
  • Patients who are at least 18 years of age.
  • Patients who have been treated with CAPD using specific solutions for at least 60 days before the baseline visit.

Exclusion

  • Patients who have received antibiotics for the treatment of an episode of peritonitis within 30 days before the screening visit. - Patients who have had acute or chronic exit-site or tunnel infection in the past 14 days, counted from the last day of infection to the screening visit.
  • Patients who have other serious diseases, such as active, or if previously treated, residual malignancy or systemic infection.
  • Patients who have had a major illness or injury requiring hospitalisation within 30 days before the baseline visit.
  • Patients who have severe malnutrition (serum albumin \< 25 g/l by bromocresol green method).
  • Patients who are participating in another study that requires Ethics Committee approval. Non-interventional studies are permitted.
  • Patients who have received an investigational product within 30 days preceding the screening visit.
  • Patients who are pregnant or lactating. (NB: Female patients of childbearing potential must have a negative urine or serum pregnancy test at the time of the screening and will be required to use a medically acceptable means of contraception during their participation in this study).
  • Patients who have a significant psychiatric disorder or mental disability that could interfere with his/her ability to provide informed consent and/or comply with protocol procedures.

Key Trial Info

Start Date :

February 1 2005

Trial Type :

INTERVENTIONAL

End Date :

July 1 2006

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT00214721

Start Date

February 1 2005

End Date

July 1 2006

Last Update

March 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

St. Paul's Hospital

Vancouver, British Columbia, Canada, V6Z 1Y6