Status:

COMPLETED

Oral Dexamethasone for Treatment of Migraine

Lead Sponsor:

The Joseph Epstein Centre for Emergency Medicine Research

Conditions:

Migraine

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The aim of this project is to determine if a single dose of oral dexamethasone at the time of discharge from the emergency department (ED) \[after successful treatment\] prevents rebound headache. Hy...

Detailed Description

Migraine headache can be a debilitating condition. A small but significant proportion of sufferers seek treatment in emergency departments \[ED\], accounting for 2-5% of ED visits.Available data sugge...

Eligibility Criteria

Inclusion

  • Consenting adult patients \[age \>17 years\] with physician-diagnosed migraine treated in the ED who are willing and able to be contacted between 48-72 hours after discharge for follow-up

Exclusion

  • Failure to consent
  • Pregnancy
  • Allergy to study medication
  • Findings inconsistent with migraine
  • Patients requiring hospital admission for further investigation and treatment
  • Patients with active peptic ulcer disease
  • Patients with Type 1 diabetes
  • Patients taking corticosteroids for another condition within 7 days
  • Active systemic fungal infection
  • Patients previously enrolled in the study

Key Trial Info

Start Date :

April 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2007

Estimated Enrollment :

63 Patients enrolled

Trial Details

Trial ID

NCT00216736

Start Date

April 1 2005

End Date

July 1 2007

Last Update

April 30 2015

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Department of Emergency Medicine, Western Health

Melbourne, Victoria, Australia, 3011

Oral Dexamethasone for Treatment of Migraine | DecenTrialz