Status:
TERMINATED
Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
University of Texas
Conditions:
Cocaine Abuse
Opiate Dependence
Eligibility:
All Genders
22-50 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to examine two medications, modafinil and citalopram, in the treatment of cocaine dependent individuals who are maintained on methadone.
Detailed Description
This is a 24-week, randomized, double-blind, placebo-controlled study examining two doses of modafinil (200 and 400 mg) and citalopram (20 and 40 mg) in the treatment of methadone maintained cocaine d...
Eligibility Criteria
Inclusion
- Meets cocaine abuse and dependence criteria (as determined by the SCID)
- Meets opiate dependence criteria (as determined by the SCID)
- In good general physical and psychiatric health (except for possible acute drug use related problems)
Exclusion
- Meets diagnostic criteria for other psychiatric disorders, including other forms of drug dependence (other than nicotine)
- Current cardiovascular disease (as determined by an electrocardiogram)
- Circumstances will not allow for completion of study (on probation or parole)
- Ethical constraints of supervision do not allow confidentiality (on probation or parole)
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT00218036
Start Date
July 1 2006
End Date
February 1 2010
Last Update
November 16 2018
Active Locations (1)
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1
University of Texas Health Science Center
Houston, Texas, United States, 77030