Status:
TERMINATED
Effect of Menstrual Cycle on Central Nervous System (CNS) Processing of Gut Stimuli in Irritable Bowel Syndrome (IBS) and Control
Lead Sponsor:
Penn State University
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
American College of Gastroenterology
Conditions:
Irritable Bowel Syndrome
Eligibility:
FEMALE
18-40 years
Brief Summary
The hypothesis of the study is that women perceive intestinal stimulation (rectal balloon distention) differently in different phases of the menstrual cycle, i.e there is an effect of hormones on the ...
Detailed Description
There is discrepancy in the literature concerning the effect of the menstrual cycle on bowel function and pain syndromes such at irritable bowel syndrome. In addition, recent studies indicate a differ...
Eligibility Criteria
Inclusion
- controls - normal bowel function
- Irritable bowel syndrome - Rome II criteria
- Normal menstrual cycle
Exclusion
- irregular menses
- pregnancy
- use of psychotropic medication
- claustrophobia
- metal implants
- metal in eyes
Key Trial Info
Start Date :
March 1 1999
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT00219531
Start Date
March 1 1999
End Date
February 1 2015
Last Update
November 29 2017
Active Locations (1)
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1
Hershey Medical Center
Hershey, Pennsylvania, United States, 17033