Status:
COMPLETED
Effect of Estrogen & Stress for Postmenopausal Women
Lead Sponsor:
Seattle Institute for Biomedical and Clinical Research
Collaborating Sponsors:
National Alliance for Research on Schizophrenia and Depression
Conditions:
Aging
Eligibility:
FEMALE
55-90 years
Phase:
PHASE2
Brief Summary
The study tests the hypothesis that estradiol administration exacerbates the effects of the stress hormone cortisol on cognition and mood for postmenopausal women. This randomized, placebo-controlled,...
Detailed Description
Estrogen replacement has been associated with improved learning and memory in both animal and human studies. However, there is some evidence to suggest that "stress" has a detrimental effect on learni...
Eligibility Criteria
Inclusion
- Postmenopausal women
Exclusion
- Current HRT use Hx of DVT current steroid user Cushing's or other similar disease Breast or uterine cancer
Key Trial Info
Start Date :
December 1 2002
Trial Type :
INTERVENTIONAL
End Date :
March 1 2005
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00220454
Start Date
December 1 2002
End Date
March 1 2005
Last Update
February 27 2007
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