Status:

COMPLETED

Investigation of the Steady State Pharmacokinetics of Sirolimus, Mycophenolat Mofetil and Fluvastatin After Renal Transplantation

Lead Sponsor:

University Hospital Schleswig-Holstein

Conditions:

Renal Transplantation

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

To investigate in renal transplant recipients the potential drug intreaction between Sirolimus, Mycophenolt Mofetil and Fluvastatin All patient enrolled in this PKI-Study had no changes in the therap...

Eligibility Criteria

Inclusion

  • renal transplant patients (18 - 65 years, inclusive)
  • cadaver and living renal transplants(1. Ntx, 2. Ntx)
  • Immunsuppression: sirolimus with or without Mycophenolat Mofetil und and fluvastatin Fluvastatin for a minimum of three months
  • writen informt consent by the patient

Exclusion

  • contraindications for statins
  • pregnancy or lactating
  • elevated liver or muscle encymes (\> 2x up to normal values: AST, ALT, bilirubine, CPK)

Key Trial Info

Start Date :

April 1 2005

Trial Type :

INTERVENTIONAL

End Date :

July 1 2005

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT00223028

Start Date

April 1 2005

End Date

July 1 2005

Last Update

October 28 2005

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