Status:
COMPLETED
Treatment of Supine Hypertension in Autonomic Failure
Lead Sponsor:
Vanderbilt University
Conditions:
Hypertension
Eligibility:
All Genders
18-80 years
Phase:
PHASE1
Brief Summary
Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe, and complicates the treatment of orthostatic hypotensio...
Detailed Description
1. Overnight Medication Trials: Patients will be studied on the GCRC while in 150 mEq/day sodium balance and on a diet free of substances which interfere with catecholamine determination. Subjects...
Eligibility Criteria
Inclusion
- Patients with autonomic failure and with supine hypertension from all races
Exclusion
- All medical students
- Pregnant women
- High-risk patients (e.g. heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction)
- History of serious allergies or asthma.
Key Trial Info
Start Date :
January 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2017
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT00223717
Start Date
January 1 2001
End Date
January 1 2017
Last Update
October 13 2017
Active Locations (1)
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1
Vanderbilt University
Nashville, Tennessee, United States, 37232