Status:

COMPLETED

Study To Evaluate The Safety, Pharmacokinetics, And Pharmacodynamics Of PF-00299804 In Patients With Advanced Solid Tumors

Lead Sponsor:

Pfizer

Conditions:

Neoplasms

Eligibility:

All Genders

18-99 years

Phase:

PHASE1

Brief Summary

The primary purpose of this study is to study the side effects of PF-00299804 and determine the highest dose that can be safely administered in patients with advanced cancer.

Eligibility Criteria

Inclusion

  • Malignant solid tumor for which there is no currently approved treatment
  • Adequate bone marrow, liver, cardiac, and kidney function

Exclusion

  • Cardiac disease
  • Anticancer therapy within 4-6 weeks (depending on therapy)
  • Pregnant or breast-feeding

Key Trial Info

Start Date :

October 11 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 23 2010

Estimated Enrollment :

121 Patients enrolled

Trial Details

Trial ID

NCT00225121

Start Date

October 11 2005

End Date

September 23 2010

Last Update

December 21 2018

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Ronald Reagan UCLA Medical Center

Los Angeles, California, United States, 90095

2

UCLA Hematology/Oncology

Los Angeles, California, United States, 90095

3

UCLA Oncology Center

Los Angeles, California, United States, 90095

4

UCLA Hematology Oncology - Santa Monica

Santa Monica, California, United States, 90404