Status:

COMPLETED

Ghrelin Levels in Pancreatic Cancer Patients

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Conditions:

Pancreatic Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The primary outcome measure for this study is plasma ghrelin level.

Detailed Description

The primary outcome measure for this study is plasma ghrelin level, and the two primary comparison are: * Patients with cachexia versus patients without cachexia * Patients with cachexia versus healt...

Eligibility Criteria

Inclusion

  • Histological or cytological proof of pancreatic adenocarcinoma
  • The control are will include healthy age-matched patients without cancer
  • The test arm will include patients with pancreatic cancer and they will divided into two groups: those with and without weight loss
  • Patients must have recovered from any major infections and/or surgical procedures

Exclusion

  • Patients with other serious medical illness like congestive heart failure, thyroid disease,liver disease or renal failure - conditions that will alter their nutritional state
  • Patients on appetite stimulant and those receiving total parenteral nutrition
  • Patients who have undergone gastrectomy or those who have gastric ulcers
  • Patients receiving active chemotherapy
  • No prior malignancy except for adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer or for which patient has been disease free for at least five years.

Key Trial Info

Start Date :

April 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2015

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT00225745

Start Date

April 1 2004

End Date

September 1 2015

Last Update

October 14 2015

Active Locations (1)

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Dartmouth Hitchcock Medical Center/Norris Cotton Cancer Center

Lebanon, New Hampshire, United States, 03756