Status:
SUSPENDED
Clinical Trial Studying the Effects of Spironolactone on Heart and Skeletal Muscle Function in Chronic Alcoholics
Lead Sponsor:
University of Aarhus
Conditions:
Cardiomyopathy, Alcoholic
Alcoholism
Eligibility:
MALE
18-65 years
Phase:
PHASE4
Brief Summary
Chronic alcoholics suffer from weak skeletal and cardiac muscle. The investigators have discovered a beneficial effect of spironolactone-treatment in that regard. Therefore, a double blind placebo con...
Detailed Description
Our department has done research into skeletal muscle function in patients with liver cirrhosis. Post-hoc analyses of one of these studies suggested that treatment with spironolactone had a positive e...
Eligibility Criteria
Inclusion
- Alcoholism, male gender
Exclusion
- Spironolactone treatment
- Tense ascites
- Hepatic encephalopathy
- Dementia
- Cancer
- Severe psychiatric disease
- Untreated thyroid disease
- Maltreated diabetes
- Spironolactone contraindications
- Kidney failure
Key Trial Info
Start Date :
April 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2011
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00226109
Start Date
April 1 2004
End Date
December 1 2011
Last Update
October 20 2010
Active Locations (1)
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1
Department of Medicine V (gastroenterology and hepatology)
Aarhus, Denmark, 9000