Status:

COMPLETED

Stress, Diurnal Cortisol, and Breast Cancer Survival

Lead Sponsor:

Stanford University

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Breast Cancer

Eligibility:

FEMALE

35+ years

Brief Summary

The purpose of this study is to learn about the effects of stress on hormones, the relationship between these hormones and cancer progression.

Detailed Description

The purpose of this study is to investigate stress and tonic activation of diurnal cortisol in aging metastatic breast cancer patients; feedback inhibition \& activation of cortisol; and stress-induce...

Eligibility Criteria

Inclusion

  • Diagnosis of recurrent or metastatic breast cancer.
  • Karnofsky of 70% or greater.
  • Proficient enough in English to be able to take questionnaires and participate in the required tasks.
  • Living within the Greater Bay Area.
  • Age 35 or older .

Exclusion

  • Positive supraclavicular lymph nodes as the only metastatic lesion at the time of initial diagnosis.
  • Active cancers within the past 10 years other than breast cancer, basal cell or squamous cell carcinomas of the skin, or in situ cancer of the cervix.
  • Any other serious medical condition that will effect short term survival
  • History of major psychiatric illness for which patient was hospitalized or medicated, with the exception of depression or anxiety
  • A diagnosis of diabetes.

Key Trial Info

Start Date :

September 8 2002

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2005

Estimated Enrollment :

115 Patients enrolled

Trial Details

Trial ID

NCT00226967

Start Date

September 8 2002

End Date

December 1 2005

Last Update

January 27 2020

Active Locations (1)

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Stanford University School of Medicine

Stanford, California, United States, 94305