Status:

COMPLETED

A Study to Assess the Concentration of Budesonide in Breast Milk From Asthmatic Women

Lead Sponsor:

AstraZeneca

Conditions:

Asthma

Eligibility:

FEMALE

Phase:

PHASE4

Brief Summary

The purpose to measure the concentration of budesonide in breast milk of asthmatic mothers on their normal maintenance treatment with budesonide (Pulmicort Turbuhaler), and to estimate the exposure of...

Eligibility Criteria

Inclusion

  • Be willing and able to comply with study procedures and provide informed consent.
  • Be breast-feeding women, aged 18 to 45 years inclusive, and having infants aged 1 to 6 months.
  • Be asthmatics that have been on maintenance treatment with Pulmicort Turbuhaler 200 or 400 µg bid for at least 3 months prior to visit

Exclusion

  • Clinically relevant abnormalities in physical examination, laboratory assessments, blood pressure or pulse as judged by the investigator.
  • Clinically relevant disease and/or abnormalities, which in the opinion of the investigator, may either put the patient or infant at risk because of participation in the study or may influence the results of the study or the patient's ability to participate in the study.
  • A suspected/manifested infection of HIV, hepatitis B or C or other infection according to WHO Risk classification 2-4

Key Trial Info

Start Date :

September 1 2004

Trial Type :

INTERVENTIONAL

End Date :

October 1 2005

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT00228475

Start Date

September 1 2004

End Date

October 1 2005

Last Update

January 24 2011

Active Locations (1)

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1

Uppsala, Sweden