Status:
TERMINATED
Comparison of 4 Diets in the Management of Overweight Patients With Vascular Disease
Lead Sponsor:
Queen's University
Conditions:
Obesity
Cardiovascular Disease
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
Type 2 diabetes can be prevented by lifestyle changes in high-risk subjects. However, controversies exist on nutritional management of diabetes. Recent data suggests that glucose and insulin responses...
Detailed Description
The primary objective of the proposed study is to compare the effectiveness of a low glycemic load diet with a Canada Food Guide Diet on weight loss in overweight subjects with cardiovascular disease....
Eligibility Criteria
Inclusion
- Men and women, aged 18 to 80 years
- BMI 25-40 kg/m2
- Documented Cardiovascular Disease as evidenced by one or more of the following:
- Coronary atherosclerosis during coronary angiography
- Documented myocardial infarction
- Carotid atherosclerosis during carotid ultrasonography
- Carotid atherosclerosis during CT angiography
- Carotid atherosclerosis during MR angiography
- Ischemic brain infarct documented on brain imaging studies
Exclusion
- Documented Type I or II diabetes mellitus (as defined by the Canadian Diabetes Association 2003 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada)
- Previous (\<5 years ago) individual or group dietary counseling with a registered dietician
- Pregnant or lactating women
- Presence of clinically important hepatic or renal disease
- Inability to communicate effectively using the English language
- Enrollment in another study concurrently
- Inability to give informed consent
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2009
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00229229
Start Date
September 1 2004
End Date
January 1 2009
Last Update
January 28 2009
Active Locations (1)
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1
Vascular Disease Prevention and Research Centre
Kingston, Ontario, Canada, K7L 5G2