Status:

COMPLETED

Improving Executive Functions After Traumatic Brain Injury (TBI): A Clinical Trial of the "Executive Plus" Program

Lead Sponsor:

Icahn School of Medicine at Mount Sinai

Collaborating Sponsors:

U.S. Department of Education

Conditions:

Traumatic Brain Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a randomized clinical trial which compares a standard day treatment program for individuals with TBI with the "Executive Plus" program; the latter emphasizes training of attention, emotional s...

Detailed Description

This is a randomized clinical trial comparing two approaches to post-TBI comprehensive day treatment. Executive Plus offers systematic treatment of post-TBI executive function deficits, through a focu...

Eligibility Criteria

Inclusion

  • At least 18 years old
  • Having a TBI as a result of a blow to the head followed by a loss of consciousness or period of being dazed and confused or a period of post traumatic amnesia or clinical signs of altered neurological function; this information must be medically documented (e.g., emergency medical record, hospital record, neuroradiological report, or neurological exam or record of physician's visit within 24 hours of injury).
  • At least three months post-injury
  • English-speaking (treatment sessions will be conducted in English)
  • Reporting executive dysfunction (by self or family)
  • Willing and able to participate in and travel to the program daily for six months
  • Oriented to time, place and person
  • Having a full-scale intelligence quotient (IQ) of at least 75
  • Having a score on the Galveston Orientation and Amnesia Test of 75 or more
  • Having communication skills adequate to participate in groups
  • Having at least a sixth-grade reading level (for testing and use of written materials)
  • Willing to complete questionnaires and interviews about mood, thinking skills, participation and the like
  • Agree to participate, i.e., completion of informed consent and Health Insurance Portability and Accountability Act (HIPAA) documents

Exclusion

  • Active substance abuse
  • Active psychosis
  • Active suicidality
  • Disruptive or violent behavior to self or others
  • Current cognitive rehabilitation (this does not include psychotherapy)
  • No impairment on the Frontal Systems Behavior Scale (FRSBE) or Wisconsin Card Sorting Test (WCST)

Key Trial Info

Start Date :

October 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2010

Estimated Enrollment :

77 Patients enrolled

Trial Details

Trial ID

NCT00233129

Start Date

October 1 2005

End Date

November 1 2010

Last Update

September 24 2013

Active Locations (1)

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1

Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10029-6574

Improving Executive Functions After Traumatic Brain Injury (TBI): A Clinical Trial of the "Executive Plus" Program | DecenTrialz