Status:
COMPLETED
Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment.
Lead Sponsor:
Azienda Sanitaria Locale 3, Torino
Conditions:
Pericarditis
Recurrence
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of the study is to determine whether colchicine is safe and effective in treatment and prevention of recurrent pericarditis after failure of conventional treatment.
Detailed Description
Colchicine is safe and effective in the management of recurrent pericarditis after failure of conventional treatment. Preliminary data (observational, non-randomized studies without a control group) h...
Eligibility Criteria
Inclusion
- Patients with the second and subsequent attack of recurrent pericarditis,
- Age≥ 18 years,
- Informed consent.
Exclusion
- Suspected neoplastic, tuberculous, or purulent etiology,
- Known severe liver disease and/or elevated transaminases \>1.5 times the upper limit of normality,
- serum creatinine\>2.5 mg/dl,
- Serum CK over the upper limit of normality or Known myopathy,
- Known gastrointestinal or blood disease,
- Pregnant or lactating women or women not protected by a contraception method,
- Known hypersensibility to colchicine,
- Treatment with colchicine at the enrolment.
Key Trial Info
Start Date :
November 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT00235079
Start Date
November 1 2005
End Date
December 1 2011
Last Update
August 7 2013
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
Cardiology Department. Maria Vittoria Hospital ASL3 Torino (Coordinating Center)
Torino, Torino, Italy, 10141
2
Azienda Ospedaliera Papa Giovanni XXIII
Bergamo, Italy
3
Ospedale Regionale
Bolzano, Italy
4
Ospedale di Rivoli
Rivoli, Italy