Status:
COMPLETED
Stem Cell Therapy in Chronic Ischemic Heart Failure
Lead Sponsor:
Odense University Hospital
Conditions:
Myocardial Ischemia
Heart Failure, Congestive
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether intracoronary bone marrow transplantation can improve left ventricular ejection fraction in patients with severe ischemic heart failure and no other o...
Detailed Description
Despite standard therapies (revascularization and drugs), patients with severe ischemic heart failure have a high morbidity and mortality. The purpose of this study is to determine whether intracoron...
Eligibility Criteria
Inclusion
- Severe ischemic heart failure and no other other option for standard therapies (revascularization and drugs),
- Stable left ventricular ejection fraction \< 40%,
- CCS class 2-3 and/or NYHA class 2-3, and
- Signed informed consent.
Exclusion
- Implantation of pacemaker (including implantable cardioverter defibrillator \[ICD\] and biventricular pacing),
- Acute myocardial infarction within 3 months,
- Atrial fibrillation, or
- Severe comorbidity that could impact the patient's short-term survival (including primary hematologic disorders)
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2007
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT00235417
Start Date
October 1 2005
End Date
May 1 2007
Last Update
June 8 2007
Active Locations (1)
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1
Department of Cardiology, Odense University Hospital
Odense, Odense C, Denmark, DK-5000