Status:

COMPLETED

A Safety and Efficacy Study for Infliximab (Remicade) With Methotrexate in Patients With Early Rheumatoid Arthritis

Lead Sponsor:

Centocor, Inc.

Conditions:

Rheumatoid Arthritis

Eligibility:

All Genders

18-75 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the efficacy and safety of infliximab (Remicade) in patients with early rheumatoid arthritis.

Detailed Description

This is a randomized, multicenter, double-blind, active-treatment-controlled, three-arm, parallel study of chronic treatment with infliximab. This study will determine whether infliximab, at two diffe...

Eligibility Criteria

Inclusion

  • Diagnosis of rheumatoid arthritis for at least 3 months and less than or equal to 3 years before screening
  • Active disease at the time of screening and pre-infusion of the drug

Exclusion

  • Pregnant, nursing, or planning a pregnancy within 18 months of enrollment
  • Incapacitated, largely or wholly bedridden, or confined to a wheelchair, or had little or no ability for self care
  • Rheumatic disease other than rheumatoid arthritis or any current systemic inflammatory condition

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2003

Estimated Enrollment :

607 Patients enrolled

Trial Details

Trial ID

NCT00236028

End Date

April 1 2003

Last Update

May 19 2011

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