Status:
COMPLETED
Effect of Positive Expiratory Pressure on Right Ventricular Function in Patients With Respiratory Distress Syndrome
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Respiratory Distress Syndrome, Adult
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The objective of this study is to analyze by trans-oesophageal echocardiography the effect on the right ventricle of positive expiratory pressure (PEP) level variations with constant plate pressure am...
Detailed Description
Background: The ventilatory strategy in patients with Adult Respiratory Distress Syndrome (ARDS) is still controversial concerning the finest level of positive expiratory pressure (PEP). In fact, PEP ...
Eligibility Criteria
Inclusion
- Intubation and artificial ventilation
- Bilateral pulmonary opacities radiological compatible with an organic pulmonary oedema
- PaO2/FiO2 report/ratio \< 200 mmHg
- Not obviously clinical or echocardiographic of rise in the pressure of ventricular filling left
- Joint presence of criteria 2, 3 and 4 since less than 72 hours
Exclusion
- Age \<18 years
- Pregnancy
- Obstructive chronic broncho-pneumonopathy
- Suspected or confirmed intracranial hypertension
- Pneumothorax
- Evolutionary oesophageal pathology
- Hemodynamic instability with need of filling vascular or modification of posology of the vasopressors in the 2 hours preceding inclusion
- PaO2/FiO2 Report/ratio \< 50 mmHg
- Amount of adrenaline or noradrenaline higher than 2 mg/hour
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
End Date :
September 1 2006
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00236262
Start Date
October 1 2005
End Date
September 1 2006
Last Update
March 26 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
HOPITAL HENRI MONDOR Department of Neurosurgery
Créteil, France, 94010