Status:

COMPLETED

A Study of the Safety of Risperidone in the Treatment of Children and Adolescents With Conduct and Other Disruptive Behavior Disorders

Lead Sponsor:

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Conditions:

Disruptive Behavior Disorder

Eligibility:

All Genders

5-17 years

Phase:

PHASE3

Brief Summary

The primary purpose of this study is to document the long-term safety of an oral formulation of risperidone in the treatment of children and adolescents with conduct and other disruptive behavior diso...

Detailed Description

This is an open-label study of an oral formulation of risperidone to be taken daily over 12 months by children and adolescents with conduct and other disruptive behavior disorders. It is an extension ...

Eligibility Criteria

Inclusion

  • Patients must have completed the double-blind study (CR002020)
  • Patients must begin the present study within 7 days of taking the last dose of medication in the prior study (CR002020)

Exclusion

  • Patients with hypersensitivity or intolerance to risperidone
  • Patients with extrapyramidal symptoms (EPS) not adequately controlled with medication
  • History of neuroleptic malignant syndrome, a rare psychotropic-drug reaction, which may be characterized by confusion, reduced consciousness, high fever or pronounced muscle stiffness
  • Significant and untreated or unstable medical illness such as diabetes, hypertension
  • serious illness of the liver, kidney, or significant disturbances of the cardiac, pulmonary, gastrointestinal, endocrine, neurological system
  • Pregnant or nursing females, or those lacking adequate contraception

Key Trial Info

Start Date :

January 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2004

Estimated Enrollment :

232 Patients enrolled

Trial Details

Trial ID

NCT00236470

Start Date

January 1 2002

End Date

July 1 2004

Last Update

June 8 2011

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