Status:

COMPLETED

A Study to Compare Ventral Incisional Hernia by Laparoscopic vs Open Repair With Mesh

Lead Sponsor:

US Department of Veterans Affairs

Conditions:

Hernia, Ventral

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this research is to compare open ventral incisional hernia repair to the laparoscopic repair with respect to complications, recurrence, pain, return to normal activities of daily living...

Detailed Description

The appearance of ventral incisional hernia (VIH) following an open abdominal operation is an important postoperative problem. While advances in anesthesia techniques, better methods to prevent surgic...

Eligibility Criteria

Inclusion

  • Patients will be eligible for enrollment into the study if they meet the following criteria: -Are 18 years of age or older -Have a diagnosis of ventral primary incisional hernia 9-225 cm2 in size. -Give informed consent for randomization - Have a negative pregnancy test. (Women)

Exclusion

  • Patients will be excluded for the following reasons: -Hernia cannot be detected on physical examination - Primary ventral or umbilical hernia - Small hernia defined as less than 9 cm2 - Giant hernia defined as greater than 225 cm2 in size - ASA class 4 or 5, or contraindications to general anesthesia - Severe co morbid conditions likely to limit survival to less than 3 years - History of malignancy within the past 5 years except for non-melanoma skin cancer - Cirrhosis with or without ascites - Presence of bowel obstruction( partial or intermittent), strangulation, peritonitis, or perforation. - Presence of local or systemic infection - Participation in another clinical trial - Emergency operation - Prisoner

Key Trial Info

Start Date :

February 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2006

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT00240188

Start Date

February 1 2004

End Date

December 1 2006

Last Update

September 16 2010

Active Locations (1)

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1

VA Boston Healthcare System, Boston

Boston, Massachusetts, United States, 02130