Status:

COMPLETED

A Study Evaluating the Efficacy and Safety of Adding Symlin® to Lantus® (Insulin Glargine) in Subjects With Type 2 Diabetes

Lead Sponsor:

AstraZeneca

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

18-75 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate the efficacy and safety of adding Symlin to an established regimen of insulin glargine in subjects with type 2 diabetes who are not achieving glycemic targets.

Eligibility Criteria

Inclusion

  • Has HbA1c \>7.0% and \<=10.5%
  • Has a body mass index (BMI) \>=25 kg/m2 and \<=45 kg/m2
  • Has received insulin glargine for 3 months prior to study start and has been on a stable dose for 1 month prior to study start
  • If taking oral antidiabetic agents, has been on a stable dose for at least 2 months

Exclusion

  • Has been previously treated with Symlin/pramlintide (or has participated in a Symlin/pramlintide clinical study)
  • Has received any investigational drug within 1 month of screening

Key Trial Info

Start Date :

October 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2006

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT00240253

Start Date

October 1 2005

End Date

June 1 2006

Last Update

March 31 2015

Active Locations (34)

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Page 1 of 9 (34 locations)

1

Research Site

Phoenix, Arizona, United States

2

Research Site

Concord, California, United States

3

Research Site

La Jolla, California, United States

4

Research Site

Los Gatos, California, United States