Status:
UNKNOWN
Hemodialysis Without Anticoagulation in Intensive Care Unit
Lead Sponsor:
Centre Hospitalier Départemental
Conditions:
Kidney Failure
Critically Ill
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to determine the safety and operative efficacy of intermittent hemodialysis without anticoagulation with saline flushes or Nephral 400ST in patients at high risk of bleedi...
Detailed Description
Hemodialysis in patients who are at high risk of bleeding complications represents a challenge of balancing the needs for establishment of an adequately functioning extracorporeal circuit for dialytic...
Eligibility Criteria
Inclusion
- age \> 18 years
- patient with high risk bleeding
- patient requiring dialytic therapy in intensive care unit
Exclusion
- Pregnancy
- History of heparin-induced thrombocytopenia or serious heparin allergy
- History of serious membrane dialysis allergy
- Treatment by any of following medications 24H within the inclusion:
- prophylactic or therapeutic anticoagulation with unfractioned heparin or low molecular weight heparin nonsteroidal anti-inflammatory agents direct thrombin inhibitors, antithrombin concentrate, activated protein C, anti-factor Xa pentasaccharide
- Treatement by acetylsalicylic acid or other antiplatelet agent excluding platelet glycoprotein IIb/IIIa antagonists 7 days within the inclusion.
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2008
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00242398
Start Date
October 1 2005
End Date
April 1 2008
Last Update
October 3 2007
Active Locations (1)
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1
CHD
La Roche-sur-Yon, France, 85925